Therapeutic use of Nigella sativa: A review

Nigella sativa also called prophetic medicine. Prophet Muhammad (Peace Be Upon on Him) recommended and used it to maintain health. Although the seeds of cumin (Cuminum cyminum L.) are widely as a spice for their distinctive aroma, they commonly in traditional medicine treat variety diseases. The literature presents ample evidence biomedical activities cumin, which have generally been ascribed its bioactive constituents such terpenes, phenols, flavonoids. Those health effects that experimentally validated discussed this review. Numerous pre-clinical clinical trials investigated efficacy using seed oil, essential main constituent thymoquinone (TQ). These investigations support use either independently or an adjunct along with conventional drugs respiratory problems, allergic rhinitis, dyspepsia, metabolic syndrome, diabetes mellitus, inflammatory diseases, different types human cancer. Multiple studies made last decades validate beneficial particularly diabetes, dyslipidemia, hypertension, disorders, possess immune stimulatory, gastroprotective, hepatoprotective, nephroprotective, neuroprotective activities. TQ is most abundant volatile oil N. seeds, medicinal properties attributed mainly TQ. All available suggests should be developed novel drug trials.